Hands-on learning with immune system activities developed for different grade levels helps children understand the intricacies of our immune system. The human body and the way we fight off infections is fascinating! The human immune system, germs, and practicing healthy hygiene habits have become topics our children have become very familiar with.
We have divided these immune system activities by two loose age levels. However, one of our goals at TheHomeschoolScientist.com is to make science fun and accessible for all types of learners and a multitude of learning differences. So, don’t hesitate to bring all of the ages together in your homeschool to do some of the activities. Younger students will walk away with new knowledge if an activity may appear above grade level. They love doing “older school”. Older siblings can learn the material really well when they work alongside siblings completing simpler activities.
The goal is to help our children enjoy learning and develop lifelong habits of seeking new knowledge.
Immune System with Activities for Kids Preschool – High School
Immune System Activities for Preschool and Early Elementary
- A short video about germs from Cincinnati Children’s. Good for K-4.
- An excellent PDF with information, activities, lessons on the immune system. It’s from Human Body Detectives.
- Germs-related free coloring pages from Kidsactivities.com
- The How the immune system works video from KidsHealth.org is a fun, animated overview.
- The Notebooking Journal that goes along with the text is a great place for students to take notes on fun pages, do crosswords that help them learn new terms, and to record experiments.
- If your kids love The Magic School Bus series, try The Magic School Bus World Of Germs science kit!
- Glitter Germs Activity
- Germ Detective Activity
- Pepper Germs Experiment
- Growing Germs Activity
Middle School and High School Immune System Activities and Resources
- Understanding the Immune System PDF from the U.S. Department of Health and Human Services, National Institute of Health.
- A 5-minute video on the immune system, its components, and how it fights off infection. Grades 5-adult.
- This immune system card game is great for middle and high school students. In the sidebar of this link are the links to the printable cards and supply list.
- This is an interesting video on natural killer cells.
- You can swab surfaces around the house and use those swabs to inoculate Petri dishes to see which surfaces have the most bacteria. Be ready for some surprises!
- An EXTENSIVE list of immunology-related terms from The International Union of Immunological Societies.
- Fighting Infections With Your Immune System
- Fighting Back! – Engineering and the Immune System
- Viral Hijackers
- Viral Packaging Activity
- Cellular Soap Opera: Anatomy & Physiology experiment
- How Big is a Virus? Video
Don’t miss the entire Human Anatomy and Physiology series from The Homeschool Scientist.